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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGI53587.1DNA methylase N-4; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (281 aa)    
Predicted Functional Partners:
KGI53586.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.927
KGI53589.1
Modification methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family.
 
     0.908
KGI54086.1
DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.765
KGI53585.1
Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
       0.705
KGI53669.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.667
KGI53588.1
HrgA protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.654
KGI54571.1
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.579
KGI53583.1
Lipopolysaccharide core biosynthesis protein LpsA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.471
KGI53584.1
NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.471
KGI54639.1
DNA adenine methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.408
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
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