STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGI53637.1Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)    
Predicted Functional Partners:
KGI54757.1
Cell division protein FtsH; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.959
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.959
KGI53011.1
ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.
   
 0.959
KGI53636.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.740
KGI54837.1
Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.685
KGI53465.1
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M16 family.
   
 0.673
KGI53508.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.557
KGI53853.1
ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.557
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.524
rsfS
Oligomerization domain protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
    
 
 0.451
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.