STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGI53362.1alpha-L-glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)    
Predicted Functional Partners:
KGI53363.1
Alkanesulfonate monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.943
KGI53361.1
5,10-methylene tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.900
KGI53364.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.593
KGI53365.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.585
KGI53366.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.577
KGI53367.1
Amino acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.577
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 0.575
pepA
Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.573
secD
Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
    
 0.573
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
    
 0.567
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
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