node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFH87865.1 | SFI31436.1 | SAMN05216206_0599 | SAMN05216206_1848 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Rrf2 family protein. | 0.595 |
SFH87865.1 | SFJ21992.1 | SAMN05216206_0599 | SAMN05216206_3728 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Adenylyltransferase and sulfurtransferase. | 0.500 |
SFH87865.1 | iscS | SAMN05216206_0599 | SAMN05216206_0600 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.999 |
SFH87865.1 | nfuA | SAMN05216206_0599 | SAMN05216206_2468 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.976 |
SFH87865.1 | thiI | SAMN05216206_0599 | SAMN05216206_3492 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | [ThiS-adenylate] sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.464 |
SFI08337.1 | SFI31436.1 | SAMN05216206_1365 | SAMN05216206_1848 | Rubredoxin. | Rrf2 family protein. | 0.489 |
SFI08337.1 | hmp | SAMN05216206_1365 | SAMN05216206_1432 | Rubredoxin. | Nitric oxide dioxygenase; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 0.904 |
SFI08337.1 | iscS | SAMN05216206_1365 | SAMN05216206_0600 | Rubredoxin. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.421 |
SFI08337.1 | nfuA | SAMN05216206_1365 | SAMN05216206_2468 | Rubredoxin. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.709 |
SFI31436.1 | SFH87865.1 | SAMN05216206_1848 | SAMN05216206_0599 | Rrf2 family protein. | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.595 |
SFI31436.1 | SFI08337.1 | SAMN05216206_1848 | SAMN05216206_1365 | Rrf2 family protein. | Rubredoxin. | 0.489 |
SFI31436.1 | SFI31468.1 | SAMN05216206_1848 | SAMN05216206_1849 | Rrf2 family protein. | FAD/FMN-containing dehydrogenase. | 0.506 |
SFI31436.1 | SFJ21992.1 | SAMN05216206_1848 | SAMN05216206_3728 | Rrf2 family protein. | Adenylyltransferase and sulfurtransferase. | 0.566 |
SFI31436.1 | SFJ27110.1 | SAMN05216206_1848 | SAMN05216206_3809 | Rrf2 family protein. | Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | 0.688 |
SFI31436.1 | hmp | SAMN05216206_1848 | SAMN05216206_1432 | Rrf2 family protein. | Nitric oxide dioxygenase; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 0.515 |
SFI31436.1 | iscS | SAMN05216206_1848 | SAMN05216206_0600 | Rrf2 family protein. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.922 |
SFI31436.1 | nfuA | SAMN05216206_1848 | SAMN05216206_2468 | Rrf2 family protein. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.698 |
SFI31436.1 | ribB | SAMN05216206_1848 | SAMN05216206_2937 | Rrf2 family protein. | GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.444 |
SFI31436.1 | thiI | SAMN05216206_1848 | SAMN05216206_3492 | Rrf2 family protein. | [ThiS-adenylate] sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.513 |
SFI31468.1 | SFI31436.1 | SAMN05216206_1849 | SAMN05216206_1848 | FAD/FMN-containing dehydrogenase. | Rrf2 family protein. | 0.506 |