Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FP66_01935DNA topoisomerase IV subunit B; Decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; Derived by automated computational analysis using gene prediction method: Protein Homology. (626 aa)    
Predicted Functional Partners:
FP66_01940
DNA topoisomerase IV subunit A; Decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
FP66_14615
DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
FP66_06735
ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.854
FP66_02970
DNA polymerase I; Has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.852
dnaK
Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.766
FP66_13440
Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.736
FP66_16170
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.710
FP66_05880
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.698
FP66_02705
DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.694
gltB
Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.659
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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