STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uvrDDNA-dependent helicase II; Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa)    
Predicted Functional Partners:
FP66_05880
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.970
FP66_02705
DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.908
FP66_12880
DNA helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.906
FP66_11910
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.898
FP66_07025
Recombinase RecA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.872
FP66_07890
DNA helicase; Unwinds double stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.850
FP66_02370
ATP-dependent DNA helicase RecG; Catalyzes branch migration in Holliday junction intermediates; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.843
FP66_10295
DNA primase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.826
FP66_02455
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.779
FP66_06055
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.774
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.