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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FP66_03035RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)    
Predicted Functional Partners:
FP66_03040
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.980
FP66_07985
Anti-sigma factor MucA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.956
FP66_06465
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.860
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.858
FP66_08380
Chemotaxis protein CheR; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.822
FP66_03030
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.810
FP66_03025
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.802
FP66_06620
DNA-directed RNA polymerase subunit alpha; Catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.792
FP66_02340
DNA-directed RNA polymerase subunit omega; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.791
FP66_03020
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.684
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.