FP66_04355 protein (Halomonas salina) - STRING interaction network

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FP66_04355

Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (1063 aa)

Predicted Functional Partners:

FP66_13540

0.968

FP66_10135

0.956

FP66_10170

0.947

FP66_06285

0.944

FP66_11875

0.936

gltB

0.933

FP66_04350

0.921

FP66_05455

0.916

FP66_03970

0.911

alr

0.908

Your Current Organism:

Halomonas salina

NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FP66_03970	FP66_04355	FP66_03970	FP66_04355	Glutamate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.911
FP66_03970	FP66_11875	FP66_03970	FP66_11875	Glutamate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.537
FP66_03970	alr	FP66_03970	FP66_12770	Glutamate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.676
FP66_03970	gltB	FP66_03970	FP66_07065	Glutamate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.955
FP66_04350	FP66_04355	FP66_04350	FP66_04355	Proline:sodium symporter PutP; Involved in the sodium dependent uptake of proline; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921
FP66_04355	FP66_03970	FP66_04355	FP66_03970	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.911
FP66_04355	FP66_04350	FP66_04355	FP66_04350	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	Proline:sodium symporter PutP; Involved in the sodium dependent uptake of proline; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921
FP66_04355	FP66_05455	FP66_04355	FP66_05455	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycine cleavage system protein H; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.916
FP66_04355	FP66_06285	FP66_04355	FP66_06285	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	Gamma-glutamyl phosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.944
FP66_04355	FP66_10135	FP66_04355	FP66_10135	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	Agmatinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.956
FP66_04355	FP66_10170	FP66_04355	FP66_10170	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	Gamma-glutamyl kinase; Catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.947
FP66_04355	FP66_11875	FP66_04355	FP66_11875	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.936
FP66_04355	FP66_13540	FP66_04355	FP66_13540	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyrroline-5-carboxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.968
FP66_04355	alr	FP66_04355	FP66_12770	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	Converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.908
FP66_04355	gltB	FP66_04355	FP66_07065	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.933
FP66_05455	FP66_04355	FP66_05455	FP66_04355	Glycine cleavage system protein H; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.916
FP66_05455	FP66_11875	FP66_05455	FP66_11875	Glycine cleavage system protein H; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.493
FP66_05455	gltB	FP66_05455	FP66_07065	Glycine cleavage system protein H; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.944
FP66_06285	FP66_04355	FP66_06285	FP66_04355	Gamma-glutamyl phosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.944
FP66_06285	FP66_10170	FP66_06285	FP66_10170	Gamma-glutamyl phosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Gamma-glutamyl kinase; Catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999

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