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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FP66_04740RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)    
Predicted Functional Partners:
groEL
Molecular chaperone GroEL; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; Derived by autom [...]
       0.720
groES
Molecular chaperone GroES; 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.671
FP66_13380
23S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.639
FP66_04725
Exlusion protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.565
rnhB
RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.547
FP66_03110
Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
      0.522
FP66_04745
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.463
FP66_10710
tRNA s(4)U8 sulfurtransferase; Catalyzes the conversion of uridine to 4-thiouridinine tRNA; also required for the synthesis of the thiazole moiety; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.439
FP66_09040
tRNA-dihydrouridine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.433
FP66_13440
Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.413
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.