Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FP66_05095GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. (608 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.721
gltB
Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.686
FP66_00150
30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.664
FP66_05090
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.648
FP66_06445
50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.613
FP66_07315
Elongation factor Ts; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.604
FP66_05400
50S ribosomal protein L35; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.586
FP66_15810
Trigger factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.575
ychF
GTP-binding protein; EngD; translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.563
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.560
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.