Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FP66_06360Dihydropteridine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)    
Predicted Functional Partners:
FP66_09360
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.906
FP66_10355
N-methylproline demethylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.781
FP66_14840
Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.781
FP66_02385
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.673
FP66_11680
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.673
FP66_11685
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.673
FP66_04355
Pyrroline-5-carboxylate dehydrogenase; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.665
FP66_15065
Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.649
FP66_08035
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.627
FP66_09475
Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.618
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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