Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FP66_07170phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)    
Predicted Functional Partners:
FP66_15355
phosphoribosyl-AMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
hisG
ATP phosphoribosyltransferase catalytic subunit; Short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
FP66_10540
ATP phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
FP66_02885
Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.989
FP66_02880
Imidazole glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.987
FP66_02895
Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.984
FP66_02890
Imidazole glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.983
FP66_00120
Histidinol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.977
FP66_07175
Preprotein translocase subunit TatA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.920
FP66_02835
Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.822
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.