Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
FP66_080702-dehydropantoate 2-reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.933
FP66_13470
Pantoate--beta-alanine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.924
FP66_08075
DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.859
FP66_05470
DNA repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.774
FP66_08080
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.697
FP66_08065
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.688
FP66_06400
biotin--acetyl-CoA-carboxylase ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.610
FP66_06900
Galactonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.580
FP66_13480
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.519
FP66_07680
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.460
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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