STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FP66_08075DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (665 aa)    
Predicted Functional Partners:
FP66_05880
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.983
FP66_08070
2-dehydropantoate 2-reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.859
FP66_06735
ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.847
FP66_07890
DNA helicase; Unwinds double stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.800
FP66_01605
Chromosome segregation protein SMC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.761
FP66_07025
Recombinase RecA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.734
FP66_06465
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.722
FP66_02090
ATP-dependent DNA helicase Rep; Single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.716
uvrD
DNA-dependent helicase II; Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.716
FP66_12880
DNA helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.716
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.