Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FP66_08115proline--tRNA ligase; Catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa)    
Predicted Functional Partners:
metG
methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.997
FP66_10190
isoleucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.993
argS
arginine--tRNA ligase; Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.991
leuS
leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; Derived by automated computational [...]
 
 0.985
FP66_07520
lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.984
FP66_09010
glutamyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.949
FP66_15760
glutamate--tRNA ligase; Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.949
FP66_05415
phenylalanyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.932
FP66_13505
glutamyl-Q tRNA(Asp) ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.894
FP66_11845
aspartyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.871
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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