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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FP66_087205,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)    
Predicted Functional Partners:
FP66_15390
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
glyA
Serine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.972
gcvT
Glycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.948
FP66_05930
Catalyzes the conversion of O-succinylhomoserine into homocysteine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.944
FP66_15840
Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.933
FP66_01820
Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.924
FP66_08755
Catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.904
FP66_00720
Homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.819
metN
DL-methionine transporter ATP-binding subunit; Part of the metNIQ transport system for methionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.806
FP66_07560
Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.799
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.