Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
FP66_087205,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)    
Predicted Functional Partners:
FP66_15390
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
glyA
Serine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.973
FP66_05450
Glycine dehydrogenase; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.955
gcvT
Glycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.941
FP66_15840
Methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.929
FP66_05930
Catalyzes the conversion of O-succinylhomoserine into homocysteine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.924
FP66_08755
Catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.914
FP66_05455
Glycine cleavage system protein H; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.907
FP66_01820
Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.885
FP66_08960
E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.872
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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