Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FP66_09415Peptidase M22; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)    
Predicted Functional Partners:
FP66_10585
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.996
FP66_10290
UGMP family protein; Universal genome maintenance protein; Kae1/Qri7/OSGEP/YgjD family protein; in Archaea, some Kae1 are found as fusion proteins similar to two distinct proteins in yeast that are involved in the KEOPS complex; kinase associated endopeptidase 1 (Kae1) and a serine/threonine protein kinase (Bud32); in Pyrococcus Kae1 has atypical AP endonuclease activity and inhibits the kinase activity of Bud32; the protein is essential in Escherichia coli and Bacillus subtilis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.988
FP66_06400
biotin--acetyl-CoA-carboxylase ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.919
FP66_09410
Ribosomal RNA small subunit methyltransferase J; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.843
FP66_09420
Adenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.722
FP66_09550
Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.598
FP66_09425
Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.570
FP66_07240
tRNA(Ile)-lysidine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.558
FP66_05575
Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.552
FP66_09855
Thiamine-monophosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.531
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
Server load: low (14%) [HD]