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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metXCatalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)    
Predicted Functional Partners:
FP66_13525
Methionine biosynthesis protein MetW; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.998
FP66_15660
O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.992
FP66_05930
Catalyzes the conversion of O-succinylhomoserine into homocysteine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.964
FP66_07560
Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.948
FP66_15390
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.930
glyA
Serine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.900
FP66_02790
Threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.899
FP66_13535
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.705
FP66_13540
Pyrroline-5-carboxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.669
FP66_13545
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.633
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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