Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FP66_14760Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)    
Predicted Functional Partners:
FP66_14755
Porphobilinogen deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.998
FP66_14765
uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.995
FP66_05850
uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.972
FP66_14770
Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.959
FP66_09755
Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.956
hemE
Uroporphyrinogen decarboxylase; Catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.948
FP66_02620
Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.752
FP66_09985
glutamyl-tRNA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.684
hemH
Ferrochelatase; Protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.641
FP66_02705
DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.633
Your Current Organism:
Halomonas salina
NCBI taxonomy Id: 42565
Other names: ATCC 49509, CIP 106092, DSM 5928, Deleya salina, H. salina, JCM 21221, strain F8-11
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