node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
M446_0168 | M446_4807 | M446_0168 | M446_4807 | PFAM: 4'-phosphopantetheinyl transferase; KEGG: gvi:gll1951 phosphopantetheinyltransferase family protein; Belongs to the P-Pant transferase superfamily. | PFAM: 4'-phosphopantetheinyl transferase; KEGG: xau:Xaut_2457 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. | 0.927 |
M446_0168 | coaE | M446_0168 | M446_1034 | PFAM: 4'-phosphopantetheinyl transferase; KEGG: gvi:gll1951 phosphopantetheinyltransferase family protein; Belongs to the P-Pant transferase superfamily. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.907 |
M446_1036 | aroE | M446_1036 | M446_1035 | Maf family protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.725 |
M446_1036 | coaE | M446_1036 | M446_1034 | Maf family protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.790 |
M446_1036 | dnaQ | M446_1036 | M446_1033 | Maf family protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.572 |
M446_4807 | M446_0168 | M446_4807 | M446_0168 | PFAM: 4'-phosphopantetheinyl transferase; KEGG: xau:Xaut_2457 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. | PFAM: 4'-phosphopantetheinyl transferase; KEGG: gvi:gll1951 phosphopantetheinyltransferase family protein; Belongs to the P-Pant transferase superfamily. | 0.927 |
M446_4807 | coaE | M446_4807 | M446_1034 | PFAM: 4'-phosphopantetheinyl transferase; KEGG: xau:Xaut_2457 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.907 |
M446_5947 | coaE | M446_5947 | M446_1034 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mex:Mext_3913 MazG family protein. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.911 |
M446_5947 | polA | M446_5947 | M446_0678 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mex:Mext_3913 MazG family protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.461 |
acpS | coaE | M446_6616 | M446_1034 | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.915 |
aroE | M446_1036 | M446_1035 | M446_1036 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Maf family protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.725 |
aroE | coaE | M446_1035 | M446_1034 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.842 |
aroE | dnaQ | M446_1035 | M446_1033 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.621 |
coaD | coaE | M446_4459 | M446_1034 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.951 |
coaD | polA | M446_4459 | M446_0678 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.448 |
coaE | M446_0168 | M446_1034 | M446_0168 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | PFAM: 4'-phosphopantetheinyl transferase; KEGG: gvi:gll1951 phosphopantetheinyltransferase family protein; Belongs to the P-Pant transferase superfamily. | 0.907 |
coaE | M446_1036 | M446_1034 | M446_1036 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Maf family protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.790 |
coaE | M446_4807 | M446_1034 | M446_4807 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | PFAM: 4'-phosphopantetheinyl transferase; KEGG: xau:Xaut_2457 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. | 0.907 |
coaE | M446_5947 | M446_1034 | M446_5947 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mex:Mext_3913 MazG family protein. | 0.911 |
coaE | acpS | M446_1034 | M446_6616 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.915 |