STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_1564PFAM: protein of unknown function DUF344; KEGG: mex:Mext_1138 protein of unknown function DUF344. (279 aa)    
Predicted Functional Partners:
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
  
 0.968
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
    
 0.910
M446_1416
PFAM: protein of unknown function DUF344; KEGG: bja:bll2813 hypothetical protein.
  
  
 
0.904
M446_6133
KEGG: dsh:Dshi_0715 protein of unknown function DUF465.
 
    0.798
M446_1562
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: mex:Mext_1140 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.743
M446_1563
TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: mex:Mext_1139 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family.
       0.743
M446_0580
PFAM: OmpW family protein; KEGG: bra:BRADO6590 conserved hypothetical protein; putative signal peptide; putative outer membrane protein precursor.
   
    0.678
M446_3584
TIGRFAM: bacteriochlorophyll 4-vinyl reductase; PFAM: 4-vinyl reductase 4VR; KEGG: rru:Rru_A0613 bacteriochlorophyll 4-vinyl reductase.
   
    0.676
M446_0311
TIGRFAM: cytochrome c oxidase accessory protein CcoG; KEGG: xau:Xaut_0463 cytochrome c oxidase cbb3 type accessory protein FixG.
   
    0.628
M446_6711
TIGRFAM: cytochrome c oxidase accessory protein CcoG; KEGG: xau:Xaut_0463 cytochrome c oxidase cbb3 type accessory protein FixG.
   
    0.628
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.