STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_1698Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: pmy:Pmen_1953 helix-turn-helix-domain containing protein, AraC type. (222 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.531
M446_1700
PFAM: PEBP family protein; KEGG: pmy:Pmen_1952 PEBP family protein.
 
    0.497
M446_5539
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: pde:Pden_4528 helix-turn-helix-domain containing protein, AraC type.
  
     0.456
M446_2995
PFAM: regulatory protein TetR; KEGG: bra:BRADO3290 putative transcriptional regulator, TetR family.
  
     0.455
M446_1699
PFAM: AMP-dependent synthetase and ligase; KEGG: olu:OSTLU_37273 predicted protein.
       0.421
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.