STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_1754TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mex:Mext_4304 folate-binding protein YgfZ; Belongs to the GcvT family. (277 aa)    
Predicted Functional Partners:
M446_4331
FeS assembly scaffold SufA; TIGRFAM: iron-sulfur cluster assembly accessory protein; FeS assembly scaffold SufA; PFAM: HesB/YadR/YfhF-family protein; KEGG: mex:Mext_3982 FeS assembly scaffold SufA; Belongs to the HesB/IscA family.
 
 
 0.651
M446_2468
TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: mex:Mext_3392 iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
 
 
 0.646
M446_0007
TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: mex:Mext_0013 glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily.
  
   
 0.622
M446_1753
KEGG: mex:Mext_4303 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3.
       0.591
M446_3583
TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: mlo:mll5942 hypothetical protein; Belongs to the HesB/IscA family.
 
 
 0.566
M446_3750
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
     
 0.564
M446_0438
PFAM: ETC complex I subunit conserved region; KEGG: mex:Mext_3134 ETC complex I subunit conserved region.
  
     0.559
M446_6494
PFAM: BolA family protein; KEGG: mex:Mext_3232 BolA family protein; Belongs to the BolA/IbaG family.
  
   
 0.554
M446_5501
TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: mex:Mext_2088 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family.
  
    0.526
M446_4813
PFAM: Methyltransferase type 11; KEGG: mex:Mext_0309 methyltransferase type 11.
  
     0.487
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.