STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_1831PFAM: Glutathione S-transferase domain; KEGG: pol:Bpro_0387 glutathione S-transferase-like. (235 aa)    
Predicted Functional Partners:
M446_1833
Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: regulatory protein Crp; KEGG: mex:Mext_0784 hypothetical protein.
  
   0.789
M446_1832
Hypothetical protein; KEGG: bpm:BURPS1710b_1545 ABC transporter, periplasmic substrate-binding protein.
       0.773
M446_3771
PFAM: Glutathione S-transferase domain; KEGG: mex:Mext_4867 glutathione S-transferase domain.
  
  
 0.708
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.694
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.627
M446_1834
PFAM: cyclic nucleotide-binding; KEGG: mex:Mext_0784 hypothetical protein.
  
   0.627
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.596
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.564
M446_2573
PFAM: Glutathione S-transferase domain; KEGG: eba:ebA4663 glutathione S-transferase family protein.
  
   
 0.559
M446_0266
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mex:Mext_0440 glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.447
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.