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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_2016PFAM: 2OG-Fe(II) oxygenase; KEGG: xau:Xaut_0346 2OG-Fe(II) oxygenase. (228 aa)    
Predicted Functional Partners:
M446_1042
Transcriptional regulator, AraC family; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein AraC type; Ada metal-binding domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: pde:Pden_4239 methylated-DNA--protein-cysteine methyltransferase.
 
  
 0.718
M446_5743
KEGG: bra:BRADO3490 hypothetical protein.
   
    0.714
M446_6167
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
    0.714
M446_2015
KEGG: mex:Mext_1969 hypothetical protein.
       0.621
M446_4755
4-hydroxyphenylpyruvate dioxygenase; PFAM: Xylose isomerase domain protein TIM barrel; KEGG: azc:AZC_1454 putative 4-hydroxyphenylpyruvate dioxygenase protein.
  
    0.518
M446_4878
PFAM: HhH-GPD family protein; KEGG: bcs:BCAN_A1687 HhH-GPD family protein.
     
 0.441
M446_2017
KEGG: mex:Mext_0444 hypothetical protein.
       0.420
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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