node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
M446_1107 | M446_5258 | M446_1107 | M446_5258 | PFAM: Chorismate mutase; KEGG: azc:AZC_4620 putative chorismate mutase. | PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_1592 prephenate dehydrogenase. | 0.606 |
M446_1107 | aroA | M446_1107 | M446_6549 | PFAM: Chorismate mutase; KEGG: azc:AZC_4620 putative chorismate mutase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.896 |
M446_1107 | aroB | M446_1107 | M446_2169 | PFAM: Chorismate mutase; KEGG: azc:AZC_4620 putative chorismate mutase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.812 |
M446_1107 | aroC | M446_1107 | M446_0392 | PFAM: Chorismate mutase; KEGG: azc:AZC_4620 putative chorismate mutase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.885 |
M446_1107 | aroE | M446_1107 | M446_1035 | PFAM: Chorismate mutase; KEGG: azc:AZC_4620 putative chorismate mutase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.488 |
M446_1107 | aroE-2 | M446_1107 | M446_4753 | PFAM: Chorismate mutase; KEGG: azc:AZC_4620 putative chorismate mutase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.488 |
M446_1107 | aroK | M446_1107 | M446_2170 | PFAM: Chorismate mutase; KEGG: azc:AZC_4620 putative chorismate mutase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.812 |
M446_1107 | aroK-2 | M446_1107 | M446_2399 | PFAM: Chorismate mutase; KEGG: azc:AZC_4620 putative chorismate mutase. | Transcriptional regulator, XRE family with shikimate kinase activity; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.658 |
M446_1107 | aroQ | M446_1107 | M446_4756 | PFAM: Chorismate mutase; KEGG: azc:AZC_4620 putative chorismate mutase. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.441 |
M446_5258 | M446_1107 | M446_5258 | M446_1107 | PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_1592 prephenate dehydrogenase. | PFAM: Chorismate mutase; KEGG: azc:AZC_4620 putative chorismate mutase. | 0.606 |
M446_5258 | aroA | M446_5258 | M446_6549 | PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_1592 prephenate dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.991 |
M446_5258 | aroB | M446_5258 | M446_2169 | PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_1592 prephenate dehydrogenase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.927 |
M446_5258 | aroC | M446_5258 | M446_0392 | PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_1592 prephenate dehydrogenase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.900 |
M446_5258 | aroK | M446_5258 | M446_2170 | PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_1592 prephenate dehydrogenase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.920 |
M446_5258 | aroK-2 | M446_5258 | M446_2399 | PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_1592 prephenate dehydrogenase. | Transcriptional regulator, XRE family with shikimate kinase activity; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.430 |
M446_5258 | aroQ | M446_5258 | M446_4756 | PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_1592 prephenate dehydrogenase. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.441 |
aroA | M446_1107 | M446_6549 | M446_1107 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | PFAM: Chorismate mutase; KEGG: azc:AZC_4620 putative chorismate mutase. | 0.896 |
aroA | M446_5258 | M446_6549 | M446_5258 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_1592 prephenate dehydrogenase. | 0.991 |
aroA | aroB | M446_6549 | M446_2169 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.996 |
aroA | aroC | M446_6549 | M446_0392 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.992 |