Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
M446_2425PFAM: protein of unknown function DUF6 transmembrane; Protein of unknown function DUF250; KEGG: sha:SH0313 hypothetical protein. (313 aa)    
Predicted Functional Partners:
M446_2426
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rpc:RPC_0171 porphobilinogen synthase; Belongs to the ALAD family.
       0.773
M446_2424
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: rpe:RPE_0278 transcriptional regulator, AraC family.
     
 0.616
M446_2423
PFAM: protein of unknown function DUF849; KEGG: fno:Fnod_0209 protein of unknown function DUF849.
 
     0.443
M446_3611
PFAM: protein of unknown function DUF6 transmembrane; KEGG: mex:Mext_4181 protein of unknown function DUF6 transmembrane.
  
     0.436
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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