STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_2478KEGG: mex:Mext_1486 protein of unknown function DUF497. (88 aa)    
Predicted Functional Partners:
M446_2477
Transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein; KEGG: sus:Acid_7034 hypothetical protein.
 
     0.734
M446_5397
KEGG: eba:ebA7093 hypothetical protein.
  
   
 0.731
M446_2312
KEGG: scl:sce5012 hypothetical protein.
  
     0.577
M446_2479
TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: rpe:RPE_2387 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
       0.549
M446_4290
KEGG: bpd:BURPS668_3046 hypothetical protein.
  
     0.482
M446_6671
KEGG: bra:BRADO6923 hypothetical protein; putative RTX family exoprotein.
  
     0.444
M446_1147
KEGG: mlo:mll1857 hypothetical protein.
  
   
 0.427
M446_5444
Plasmid maintenance system antidote protein, XRE family; TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: pde:Pden_1963 plasmid maintenance system antidote protein, XRE family.
 
     0.419
M446_1148
KEGG: mex:Mext_3283 hypothetical protein.
 
   
 0.415
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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