STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_4244PFAM: alpha/beta hydrolase fold; KEGG: psa:PST_2922 hydrolase, alpha/beta fold family. (331 aa)    
Predicted Functional Partners:
M446_0317
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase.
 
 
 0.799
M446_6079
PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce8262 non-ribosomal peptide synthetase.
  
 
 0.763
M446_2875
PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; phosphopantetheine-binding; KEGG: pol:Bpro_3393 AMP-dependent synthetase and ligase.
  
 
 0.694
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
   0.644
M446_4245
PFAM: peptidase S45 penicillin amidase; KEGG: oih:OB3304 penicillin acylase.
       0.524
M446_0170
Beta-ketoacyl synthase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sen:SACE_2630 modular polyketide synthase.
  
 
 0.513
M446_0172
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sen:SACE_2875 modular polyketide synthase-.
  
 
 0.513
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.