Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
M446_46975-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: rpd:RPD_2368 5-oxoprolinase (ATP-hydrolyzing). (692 aa)    
Predicted Functional Partners:
M446_1934
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase B/oxoprolinase; KEGG: azc:AZC_2116 hydantoin utilization protein B.
 0.999
M446_1981
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase B/oxoprolinase; KEGG: mlo:mlr4788 N-methylhydantoinase B.
 0.999
M446_4696
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase B/oxoprolinase; KEGG: rpd:RPD_2367 5-oxoprolinase (ATP-hydrolyzing).
 0.999
M446_5647
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase B/oxoprolinase; KEGG: oan:Oant_4582 5-oxoprolinase (ATP-hydrolyzing).
 0.999
M446_1935
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: azc:AZC_2117 hydantoin utilization protein A.
  
  
 
0.915
M446_5648
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: oan:Oant_4581 5-oxoprolinase (ATP-hydrolyzing).
  
  
 
0.915
M446_1980
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: mlo:mlr4786 N-methylhydantoinase A (mikimopine-lactam hydrogenase).
  
  
 
0.912
M446_0933
PFAM: Amidohydrolase 3; KEGG: reu:Reut_B3993 cytosine deaminase.
     
  0.900
M446_3603
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: rpb:RPB_2084 amidohydrolase.
     
  0.900
M446_4698
PFAM: Extracellular ligand-binding receptor; KEGG: mex:Mext_2534 extracellular ligand-binding receptor.
       0.559
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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