Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
M446_4792PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: mex:Mext_1729 molybdopterin dehydrogenase FAD-binding. (275 aa)    
Predicted Functional Partners:
M446_4793
PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mex:Mext_1728 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding.
 
 0.998
M446_1983
PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mag:amb1483 aldehyde oxidoreductase.
 
 0.981
M446_5697
PFAM: ferredoxin; [2Fe-2S]-binding domain protein; carbon monoxide dehydrogenase subunit G; KEGG: xau:Xaut_0646 (2Fe-2S)-binding domain protein.
 
 0.728
M446_5699
PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: xau:Xaut_0648 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding.
 
 0.683
M446_0550
PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: mex:Mext_1289 carbon-monoxide dehydrogenase (acceptor).
 
 0.647
M446_5448
KEGG: mex:Mext_1056 xanthine dehydrogenase accessory factor.
 
  
 0.646
M446_1301
PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; cyclase/dehydrase; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; carbon monoxide dehydrogenase subunit G; KEGG: bja:blr3533 putative carbon monoxide dehydrogenase large chain.
 
 0.634
M446_5447
PFAM: protein of unknown function DUF182; KEGG: mex:Mext_1055 protein of unknown function DUF182.
 
  
 0.604
M446_3111
PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: acr:Acry_2211 carbon-monoxide dehydrogenase (acceptor).
 
 0.593
M446_0551
PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: mex:Mext_1290 (2Fe-2S)-binding domain protein.
 
 0.589
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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