Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
M446_5002PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: mex:Mext_3475 fumarylacetoacetate (FAA) hydrolase. (232 aa)    
Predicted Functional Partners:
M446_2715
KEGG: ccr:CC_2531 fumarylacetoacetate hydrolase family protein.
     
 0.904
M446_5203
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: bbt:BBta_5977 putative fumarylacetoacetate hydrolase family protein.
  
  
 
0.902
M446_2533
Fumarylacetoacetase; KEGG: xau:Xaut_3332 fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase; Domain of unknown function DUF1969.
     
 0.900
M446_5001
PFAM: NUDIX hydrolase; KEGG: mex:Mext_3476 NUDIX hydrolase.
       0.853
M446_6038
TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: mex:Mext_3600 succinate dehydrogenase, cytochrome b556 subunit.
  
 
  0.833
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.822
M446_6040
KEGG: mex:Mext_3602 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.817
M446_6042
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mex:Mext_3604 succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
  0.810
M446_6039
TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: mex:Mext_3601 succinate dehydrogenase, hydrophobic membrane anchor protein.
   
 
  0.806
M446_5003
PFAM: FAD linked oxidase domain protein; KEGG: mex:Mext_3474 FAD linked oxidase domain protein.
 
     0.773
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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