STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_6206KEGG: bja:blr3168 oxidoredutase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding. (293 aa)    
Predicted Functional Partners:
M446_5205
Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: mex:Mext_2747 hydroxypyruvate reductase.
 
  
 0.919
M446_3126
PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: mes:Meso_2516 6-phosphogluconate dehydrogenase, NAD-binding.
  
  
 
0.909
M446_2232
Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mex:Mext_0421 glyoxylate reductase.
    
 0.903
M446_6553
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mex:Mext_1796 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding.
    
 0.903
M446_0667
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rpb:RPB_1647 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
    
  0.900
M446_3560
PFAM: 6-phosphogluconate dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bam:Bamb_4327 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
    
  0.900
M446_6205
PFAM: HpcH/HpaI aldolase; KEGG: azc:AZC_0555 2-dehydro-3-deoxyglucarate aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
  0.897
M446_6204
KEGG: bbt:BBta_6488 (D)-glucarate dehydratase 1; TIGRFAM: glucarate dehydratase; PFAM: Mandelate racemase/muconate lactonizing protein.
 
    0.740
M446_4655
3-oxoadipate enol-lactonase; TIGRFAM: 4-carboxymuconolactone decarboxylase; 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold; Carboxymuconolactone decarboxylase; KEGG: reh:H16_B2288 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase.
  
  
 0.508
M446_2625
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: xau:Xaut_1026 hydroxypyruvate isomerase; Belongs to the hyi family.
  
 0.450
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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