node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SET07792.1 | SET08316.1 | SAMN05660297_01325 | SAMN05660297_01344 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.966 |
SET07792.1 | SET11028.1 | SAMN05660297_01325 | SAMN05660297_01437 | Dihydrolipoamide dehydrogenase. | Glutamate synthase (NADPH/NADH) large chain. | 0.915 |
SET07792.1 | SET32880.1 | SAMN05660297_01325 | SAMN05660297_02037 | Dihydrolipoamide dehydrogenase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.408 |
SET07792.1 | SET53087.1 | SAMN05660297_01325 | SAMN05660297_02699 | Dihydrolipoamide dehydrogenase. | Phosphoribosylformylglycinamidine synthase. | 0.478 |
SET07792.1 | SET76603.1 | SAMN05660297_01325 | SAMN05660297_03435 | Dihydrolipoamide dehydrogenase. | Formate dehydrogenase major subunit. | 0.825 |
SET07792.1 | gcvH | SAMN05660297_01325 | SAMN05660297_01157 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.959 |
SET07792.1 | gcvPA | SAMN05660297_01325 | SAMN05660297_01156 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.949 |
SET07792.1 | gcvPB | SAMN05660297_01325 | SAMN05660297_01155 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.951 |
SET07792.1 | gcvT | SAMN05660297_01325 | SAMN05660297_01158 | Dihydrolipoamide dehydrogenase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.953 |
SET07792.1 | glyA | SAMN05660297_01325 | SAMN05660297_00428 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.850 |
SET08316.1 | SET07792.1 | SAMN05660297_01344 | SAMN05660297_01325 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.966 |
SET08316.1 | SET11028.1 | SAMN05660297_01344 | SAMN05660297_01437 | Dihydrolipoamide dehydrogenase. | Glutamate synthase (NADPH/NADH) large chain. | 0.916 |
SET08316.1 | SET32880.1 | SAMN05660297_01344 | SAMN05660297_02037 | Dihydrolipoamide dehydrogenase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.498 |
SET08316.1 | SET53087.1 | SAMN05660297_01344 | SAMN05660297_02699 | Dihydrolipoamide dehydrogenase. | Phosphoribosylformylglycinamidine synthase. | 0.898 |
SET08316.1 | SET76603.1 | SAMN05660297_01344 | SAMN05660297_03435 | Dihydrolipoamide dehydrogenase. | Formate dehydrogenase major subunit. | 0.927 |
SET08316.1 | gcvH | SAMN05660297_01344 | SAMN05660297_01157 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
SET08316.1 | gcvPA | SAMN05660297_01344 | SAMN05660297_01156 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.960 |
SET08316.1 | gcvPB | SAMN05660297_01344 | SAMN05660297_01155 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.965 |
SET08316.1 | gcvT | SAMN05660297_01344 | SAMN05660297_01158 | Dihydrolipoamide dehydrogenase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
SET08316.1 | glyA | SAMN05660297_01344 | SAMN05660297_00428 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.913 |