node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SES63536.1 | SET32378.1 | SAMN05660297_00018 | SAMN05660297_02011 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.867 |
SES63536.1 | SET36796.1 | SAMN05660297_00018 | SAMN05660297_02173 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. | Hypothetical protein. | 0.698 |
SES63536.1 | SET38924.1 | SAMN05660297_00018 | SAMN05660297_02277 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.781 |
SES63536.1 | SET67752.1 | SAMN05660297_00018 | SAMN05660297_03118 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. | Magnesium transporter; Acts as a magnesium transporter. | 0.562 |
SES63536.1 | guaA | SAMN05660297_00018 | SAMN05660297_00820 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.852 |
SES63536.1 | guaB | SAMN05660297_00018 | SAMN05660297_00819 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.856 |
SES63536.1 | purA | SAMN05660297_00018 | SAMN05660297_01211 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.804 |
SES63536.1 | purH | SAMN05660297_00018 | SAMN05660297_00831 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. | IMP cyclohydrolase. | 0.790 |
SET11028.1 | SET32378.1 | SAMN05660297_01437 | SAMN05660297_02011 | Glutamate synthase (NADPH/NADH) large chain. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.419 |
SET11028.1 | SET36796.1 | SAMN05660297_01437 | SAMN05660297_02173 | Glutamate synthase (NADPH/NADH) large chain. | Hypothetical protein. | 0.688 |
SET11028.1 | SET38924.1 | SAMN05660297_01437 | SAMN05660297_02277 | Glutamate synthase (NADPH/NADH) large chain. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.704 |
SET11028.1 | SET67752.1 | SAMN05660297_01437 | SAMN05660297_03118 | Glutamate synthase (NADPH/NADH) large chain. | Magnesium transporter; Acts as a magnesium transporter. | 0.571 |
SET11028.1 | guaA | SAMN05660297_01437 | SAMN05660297_00820 | Glutamate synthase (NADPH/NADH) large chain. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.958 |
SET11028.1 | guaB | SAMN05660297_01437 | SAMN05660297_00819 | Glutamate synthase (NADPH/NADH) large chain. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.948 |
SET11028.1 | purA | SAMN05660297_01437 | SAMN05660297_01211 | Glutamate synthase (NADPH/NADH) large chain. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.735 |
SET11028.1 | purH | SAMN05660297_01437 | SAMN05660297_00831 | Glutamate synthase (NADPH/NADH) large chain. | IMP cyclohydrolase. | 0.862 |
SET32378.1 | SES63536.1 | SAMN05660297_02011 | SAMN05660297_00018 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.867 |
SET32378.1 | SET11028.1 | SAMN05660297_02011 | SAMN05660297_01437 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Glutamate synthase (NADPH/NADH) large chain. | 0.419 |
SET32378.1 | SET36796.1 | SAMN05660297_02011 | SAMN05660297_02173 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Hypothetical protein. | 0.610 |
SET32378.1 | SET38924.1 | SAMN05660297_02011 | SAMN05660297_02277 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.791 |