node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACB22483.1 | ACB22558.1 | Mrad2831_0472 | Mrad2831_0547 | KEGG: mex:Mext_3313 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.986 |
ACB22483.1 | carA | Mrad2831_0472 | Mrad2831_0570 | KEGG: mex:Mext_3313 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: mex:Mext_0615 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.974 |
ACB22483.1 | carB | Mrad2831_0472 | Mrad2831_0567 | KEGG: mex:Mext_3313 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: mex:Mext_1088 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.977 |
ACB22483.1 | purA | Mrad2831_0472 | Mrad2831_5638 | KEGG: mex:Mext_3313 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.424 |
ACB22483.1 | pyrB | Mrad2831_0472 | Mrad2831_1010 | KEGG: mex:Mext_3313 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. | KEGG: mex:Mext_3312 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
ACB22483.1 | pyrC | Mrad2831_0472 | Mrad2831_5321 | KEGG: mex:Mext_3313 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.928 |
ACB22483.1 | pyrE | Mrad2831_0472 | Mrad2831_5320 | KEGG: mex:Mext_3313 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.863 |
ACB22483.1 | pyrF | Mrad2831_0472 | Mrad2831_1753 | KEGG: mex:Mext_3313 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.880 |
ACB22558.1 | ACB22483.1 | Mrad2831_0547 | Mrad2831_0472 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | KEGG: mex:Mext_3313 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. | 0.986 |
ACB22558.1 | ACB25915.1 | Mrad2831_0547 | Mrad2831_3941 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | KEGG: bja:blr3295 dihydropyrimidinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase; Amidohydrolase 3. | 0.876 |
ACB22558.1 | carA | Mrad2831_0547 | Mrad2831_0570 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: mex:Mext_0615 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.950 |
ACB22558.1 | carB | Mrad2831_0547 | Mrad2831_0567 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: mex:Mext_1088 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.969 |
ACB22558.1 | purA | Mrad2831_0547 | Mrad2831_5638 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.569 |
ACB22558.1 | pyrB | Mrad2831_0547 | Mrad2831_1010 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | KEGG: mex:Mext_3312 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.960 |
ACB22558.1 | pyrC | Mrad2831_0547 | Mrad2831_5321 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.989 |
ACB22558.1 | pyrE | Mrad2831_0547 | Mrad2831_5320 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.995 |
ACB22558.1 | pyrF | Mrad2831_0547 | Mrad2831_1753 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.948 |
ACB25170.1 | purA | Mrad2831_3188 | Mrad2831_5638 | KEGG: mex:Mext_4868 asparagine synthase family amidotransferase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); asparagine synthase family amidotransferase; PFAM: glutamine amidotransferase class-II; asparagine synthase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.934 |
ACB25170.1 | pyrB | Mrad2831_3188 | Mrad2831_1010 | KEGG: mex:Mext_4868 asparagine synthase family amidotransferase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); asparagine synthase family amidotransferase; PFAM: glutamine amidotransferase class-II; asparagine synthase. | KEGG: mex:Mext_3312 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.931 |
ACB25915.1 | ACB22558.1 | Mrad2831_3941 | Mrad2831_0547 | KEGG: bja:blr3295 dihydropyrimidinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase; Amidohydrolase 3. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.876 |