node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACB22182.1 | ACB22589.1 | Mrad2831_0155 | Mrad2831_0578 | PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mex:Mext_0604 thiamine biosynthesis protein ThiS. | 0.836 |
ACB22182.1 | ACB23953.1 | Mrad2831_0155 | Mrad2831_1958 | PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase. | KEGG: azc:AZC_1826 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.981 |
ACB22182.1 | ACB25139.1 | Mrad2831_0155 | Mrad2831_3157 | PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: mex:Mext_1632 UBA/ThiF-type NAD/FAD binding protein. | 0.742 |
ACB22182.1 | ACB25370.1 | Mrad2831_0155 | Mrad2831_3392 | PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase. | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.566 |
ACB22182.1 | guaB | Mrad2831_0155 | Mrad2831_0084 | PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.448 |
ACB22182.1 | thiC | Mrad2831_0155 | Mrad2831_3185 | PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.851 |
ACB22182.1 | thiE | Mrad2831_0155 | Mrad2831_0580 | PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase. | Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.900 |
ACB22182.1 | thiE-2 | Mrad2831_0155 | Mrad2831_1959 | PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.900 |
ACB22182.1 | thiG | Mrad2831_0155 | Mrad2831_0579 | PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.856 |
ACB22589.1 | ACB22182.1 | Mrad2831_0578 | Mrad2831_0155 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mex:Mext_0604 thiamine biosynthesis protein ThiS. | PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase. | 0.836 |
ACB22589.1 | ACB23953.1 | Mrad2831_0578 | Mrad2831_1958 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mex:Mext_0604 thiamine biosynthesis protein ThiS. | KEGG: azc:AZC_1826 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.840 |
ACB22589.1 | ACB25139.1 | Mrad2831_0578 | Mrad2831_3157 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mex:Mext_0604 thiamine biosynthesis protein ThiS. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: mex:Mext_1632 UBA/ThiF-type NAD/FAD binding protein. | 0.952 |
ACB22589.1 | ACB25370.1 | Mrad2831_0578 | Mrad2831_3392 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mex:Mext_0604 thiamine biosynthesis protein ThiS. | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.784 |
ACB22589.1 | thiC | Mrad2831_0578 | Mrad2831_3185 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mex:Mext_0604 thiamine biosynthesis protein ThiS. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.859 |
ACB22589.1 | thiE | Mrad2831_0578 | Mrad2831_0580 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mex:Mext_0604 thiamine biosynthesis protein ThiS. | Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.962 |
ACB22589.1 | thiE-2 | Mrad2831_0578 | Mrad2831_1959 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mex:Mext_0604 thiamine biosynthesis protein ThiS. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.836 |
ACB22589.1 | thiG | Mrad2831_0578 | Mrad2831_0579 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mex:Mext_0604 thiamine biosynthesis protein ThiS. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.997 |
ACB23953.1 | ACB22182.1 | Mrad2831_1958 | Mrad2831_0155 | KEGG: azc:AZC_1826 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | PFAM: thiamine monophosphate synthase; KEGG: mex:Mext_2370 thiamine monophosphate synthase. | 0.981 |
ACB23953.1 | ACB22589.1 | Mrad2831_1958 | Mrad2831_0578 | KEGG: azc:AZC_1826 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: mex:Mext_0604 thiamine biosynthesis protein ThiS. | 0.840 |
ACB23953.1 | ACB25139.1 | Mrad2831_1958 | Mrad2831_3157 | KEGG: azc:AZC_1826 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: mex:Mext_1632 UBA/ThiF-type NAD/FAD binding protein. | 0.868 |