STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACB25885.1PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: mex:Mext_4771 GCN5-related N-acetyltransferase. (891 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.712
ACB23343.1
KEGG: bbt:BBta_1093 L-ornithine 5-monooxygenase (L-ornithine N5-oxygenase).
  
  
 0.683
ACB24175.1
Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: acr:Acry_1769 transcriptional regulator, DeoR family.
    
   0.683
ACB25249.1
Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: smd:Smed_2902 transcriptional regulator, DeoR family.
    
   0.683
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.670
ACB24737.1
PFAM: histone deacetylase superfamily; KEGG: mex:Mext_2993 histone deacetylase superfamily.
 
     0.619
ACB22509.1
PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: mex:Mext_0827 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), phosphate acetyltransferase.
     
 0.585
ACB22962.1
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase.
  
  
 0.566
ACB23076.1
PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_1958 AMP-dependent synthetase and ligase.
 
   
 0.566
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
   
 0.480
Your Current Organism:
Methylobacterium radiotolerans
NCBI taxonomy Id: 426355
Other names: M. radiotolerans JCM 2831, Methylobacterium radiotolerans ATCC 27329, Methylobacterium radiotolerans IAM 12098, Methylobacterium radiotolerans JCM 2831, Methylobacterium radiotolerans str. JCM 2831, Methylobacterium radiotolerans strain JCM 2831
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