node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACB23625.1 | ACB25970.1 | Mrad2831_1630 | Mrad2831_3996 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mex:Mext_3913 MazG family protein. | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.912 |
ACB23625.1 | ACB26990.1 | Mrad2831_1630 | Mrad2831_5032 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mex:Mext_3913 MazG family protein. | PFAM: glutamine amidotransferase class-I; KEGG: mex:Mext_3437 glutamine amidotransferase class-I. | 0.900 |
ACB23625.1 | apt | Mrad2831_1630 | Mrad2831_3506 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mex:Mext_3913 MazG family protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.908 |
ACB23625.1 | guaA | Mrad2831_1630 | Mrad2831_0451 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mex:Mext_3913 MazG family protein. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.907 |
ACB25899.1 | ACB25970.1 | Mrad2831_3925 | Mrad2831_3996 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.938 |
ACB25899.1 | ade | Mrad2831_3925 | Mrad2831_2849 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | KEGG: atc:AGR_C_4165 adenine deaminase; TIGRFAM: adenine deaminase; PFAM: amidohydrolase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.905 |
ACB25899.1 | apt | Mrad2831_3925 | Mrad2831_3506 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.946 |
ACB25899.1 | guaA | Mrad2831_3925 | Mrad2831_0451 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.600 |
ACB25899.1 | guaB | Mrad2831_3925 | Mrad2831_0084 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.565 |
ACB25970.1 | ACB23625.1 | Mrad2831_3996 | Mrad2831_1630 | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mex:Mext_3913 MazG family protein. | 0.912 |
ACB25970.1 | ACB25899.1 | Mrad2831_3996 | Mrad2831_3925 | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.938 |
ACB25970.1 | ACB26990.1 | Mrad2831_3996 | Mrad2831_5032 | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | PFAM: glutamine amidotransferase class-I; KEGG: mex:Mext_3437 glutamine amidotransferase class-I. | 0.928 |
ACB25970.1 | ade | Mrad2831_3996 | Mrad2831_2849 | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | KEGG: atc:AGR_C_4165 adenine deaminase; TIGRFAM: adenine deaminase; PFAM: amidohydrolase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.921 |
ACB25970.1 | apt | Mrad2831_3996 | Mrad2831_3506 | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.943 |
ACB25970.1 | gmk | Mrad2831_3996 | Mrad2831_3720 | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.944 |
ACB25970.1 | guaA | Mrad2831_3996 | Mrad2831_0451 | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.953 |
ACB25970.1 | guaB | Mrad2831_3996 | Mrad2831_0084 | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.951 |
ACB25970.1 | purA | Mrad2831_3996 | Mrad2831_5638 | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.947 |
ACB25970.1 | purH | Mrad2831_3996 | Mrad2831_5593 | KEGG: mex:Mext_2861 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | KEGG: mex:Mext_2566 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.939 |
ACB26990.1 | ACB23625.1 | Mrad2831_5032 | Mrad2831_1630 | PFAM: glutamine amidotransferase class-I; KEGG: mex:Mext_3437 glutamine amidotransferase class-I. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mex:Mext_3913 MazG family protein. | 0.900 |