STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccmAHeme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (212 aa)    
Predicted Functional Partners:
ACB27713.1
Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 0.999
ccmC
Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.991
ccmE
CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.874
ACB26952.1
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
 
   
 0.802
ACB26951.1
TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: mex:Mext_1406 cytochrome c assembly protein.
 
   
 0.794
ACB27287.1
TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain; KEGG: mex:Mext_2614 periplasmic protein thiol--disulphide oxidoreductase DsbE.
 
   
 0.687
ACB24759.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mex:Mext_1808 ABC transporter related.
  
     0.627
ACB27711.1
KEGG: mex:Mext_2636 hypothetical protein.
       0.583
ACB26949.1
TIGRFAM: cytochrome c-type biogenesis protein CcmI; KEGG: mex:Mext_1408 cytochrome c-type biogenesis protein CcmI.
 
   
 0.565
ACB25317.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mex:Mext_0331 ABC transporter related.
  
     0.564
Your Current Organism:
Methylobacterium radiotolerans
NCBI taxonomy Id: 426355
Other names: M. radiotolerans JCM 2831, Methylobacterium radiotolerans ATCC 27329, Methylobacterium radiotolerans IAM 12098, Methylobacterium radiotolerans JCM 2831, Methylobacterium radiotolerans str. JCM 2831, Methylobacterium radiotolerans strain JCM 2831
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