STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABR66214.1TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: mmp:MMP0148 acetyl-CoA synthetase, AMP-forming. (636 aa)    
Predicted Functional Partners:
cdhE
CO dehydrogenase/acetyl-CoA synthase delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
  
 
 0.968
ABR65528.1
PFAM: Thiolase; KEGG: mmp:MMP1212 acetyl-CoA acyltransferase.
  
 
 0.967
ABR66319.1
PFAM: CoA-binding domain protein; KEGG: mmp:MMP0253 acetyl-CoA synthetase (ADP-forming), alpha and beta subunits.
    
 0.967
ABR66411.1
PFAM: GPR1/FUN34/yaaH family protein; KEGG: mmp:MMP0348 hypothetical protein.
  
  
 0.960
cdhC
CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
  
 
 0.936
ABR65386.1
TIGRFAM: isopropylmalate/citramalate/homocitrate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: mmp:MMP1063 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.936
ABR66219.1
TIGRFAM: isopropylmalate/citramalate/homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mmp:MMP0153 2-oxosuberate synthase, first step; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.936
cdhD
CO dehydrogenase/acetyl-CoA synthase, delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
  
 
 0.935
ABR66067.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mmp:MMP0003 2-oxoglutarate oxidoreductase alpha subunit.
  
 
 0.934
ABR65816.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mmp:MMP1505 pyruvate oxidoreductase (synthase) subunit alpha.
  
 
 0.932
Your Current Organism:
Methanococcus maripaludis C7
NCBI taxonomy Id: 426368
Other names: M. maripaludis C7, Methanococcus maripaludis str. C7, Methanococcus maripaludis strain C7
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