STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTRG_10269Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (545 aa)    
Predicted Functional Partners:
PTRG_03130
GMP synthase.
 
 0.995
PTRG_03373
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family.
  
 
 0.985
PTRG_03984
Bifunctional purine biosynthesis protein ADE16.
  
 
 0.929
PTRG_10051
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
  
 
 0.921
PTRG_08116
AMP deaminase 3; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
  
 0.911
PTRG_07719
Glutamine amidotransferase type-1 domain-containing protein.
  
 
 0.910
PTRG_09054
Glutamine amidotransferase type-1 domain-containing protein.
  
 
 0.910
PTRG_09777
Glutamine amidotransferase type-1 domain-containing protein.
  
 
 0.910
PTRG_08426
Hypoxanthine guanine phosphoribosyltransferase.
  
 
 0.901
PTRG_05505
Urease accessory protein UreD.
  
 
 0.899
Your Current Organism:
Pyrenophora triticirepentis
NCBI taxonomy Id: 426418
Other names: P. tritici-repentis Pt-1C-BFP, Pyrenophora tritici-repentis Pt-1C-BFP
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