STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTRG_10922Uncharacterized protein. (267 aa)    
Predicted Functional Partners:
fen1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 
 0.754
PTRG_00585
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.736
PTRG_06451
Exodeoxyribonuclease 1.
  
 
 0.705
PTRG_04512
DNA repair protein rad50.
  
 
 0.687
PTRG_10572
Poly [ADP-ribose] polymerase.
     
 0.668
PTRG_01524
Zn(2)-C6 fungal-type domain-containing protein.
    
 0.626
PTRG_00942
Formamidopyrimidine-DNA glycosylase.
  
  
 0.601
PTRG_07624
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
   
 
 0.582
PTRG_07140
DNA-repair protein rad13.
  
 
 0.560
PTRG_00806
Mating-type switching protein swi10.
     
 0.556
Your Current Organism:
Pyrenophora triticirepentis
NCBI taxonomy Id: 426418
Other names: P. tritici-repentis Pt-1C-BFP, Pyrenophora tritici-repentis Pt-1C-BFP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.