STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDJ81692.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (450 aa)    
Predicted Functional Partners:
SDJ81650.1
Pyruvate dehydrogenase E1 component beta subunit.
 
 0.998
SDJ81732.1
Dihydrolipoamide dehydrogenase.
 0.998
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.994
SDK03509.1
2-oxoisovalerate dehydrogenase E1 component beta subunit.
 
 0.992
SDK03556.1
2-oxoisovalerate dehydrogenase E1 component alpha subunit.
 
 0.986
SDK03599.1
Dihydrolipoamide dehydrogenase.
 0.978
merA
Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 0.932
SDJ87188.1
NADPH-glutathione reductase.
 0.920
SDK84744.1
3-hydroxyacyl-CoA dehydrogenase.
  
 0.881
SDK52750.1
Acetaldehyde dehydrogenase / alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.877
Your Current Organism:
Alkalibacterium thalassium
NCBI taxonomy Id: 426701
Other names: A. thalassium, Alkalibacterium thalassium Ishikawa et al. 2009, DSM 19181, NBRC 103241, NRIC 0718, strain T117-1-2
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