STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDK55691.1DNA replication protein. (237 aa)    
Predicted Functional Partners:
nth
DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
  
 0.907
SDJ74797.1
Primosomal protein DnaI.
 
  
 0.801
SDK55792.1
Uncharacterized protein YpmB.
 
     0.763
SDJ74837.1
Replicative DNA helicase loader DnaB.
  
   
 0.753
SDK55923.1
NTP pyrophosphatase, house-cleaning of non-canonical NTPs.
 
     0.711
dinG
ATP-dependent DNA helicase DinG; 3'-5' exonuclease.
 
  
 0.695
rpoE
DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
  
     0.657
asnS
asparaginyl-tRNA synthetase.
  
    0.595
SDK92113.1
Uncharacterized protein YrzB, UPF0473 family; Belongs to the UPF0473 family.
  
     0.586
SDK13076.1
YbbR domain-containing protein.
 
     0.585
Your Current Organism:
Alkalibacterium thalassium
NCBI taxonomy Id: 426701
Other names: A. thalassium, Alkalibacterium thalassium Ishikawa et al. 2009, DSM 19181, NBRC 103241, NRIC 0718, strain T117-1-2
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