STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FNYG_04863BRCT domain-containing protein. (453 aa)    
Predicted Functional Partners:
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.794
FNYG_12268
Uncharacterized protein.
    
 0.784
FNYG_11259
Uncharacterized protein.
    
 0.784
FNYG_10953
Zn(2)-C6 fungal-type domain-containing protein.
    
 0.784
FNYG_00906
Uncharacterized protein.
    
 0.784
FNYG_00038
Uncharacterized protein.
    
 0.784
FNYG_08501
WD_REPEATS_REGION domain-containing protein.
    
 0.768
FNYG_11034
Uncharacterized protein.
    
 0.758
FNYG_09112
BRCT domain-containing protein.
    
 0.754
FNYG_01906
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    
 0.754
Your Current Organism:
Fusarium nygamai
NCBI taxonomy Id: 42673
Other names: ATCC 58555, BBA 69862, CBS 749.97, DAOM 225148, F. nygamai, Gibberella nygamai, IMI 375354, NRRL 13448
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