STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDE47239.1Acyl-CoA hydrolase. (423 aa)    
Predicted Functional Partners:
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.923
SDE51266.1
Heterodimeric methylmalonyl-CoA mutase large subunit precursor.
  
 
 0.852
SDE94446.1
3-hydroxyacyl-CoA dehydrogenase.
  
 0.733
SDE64013.1
Acetoin utilization protein AcuC.
      0.708
SDE62062.1
Citrate synthase; Belongs to the citrate synthase family.
   
 0.663
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.629
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 0.596
SDE46031.1
Succinate dehydrogenase subunit A.
   
 
 0.571
SDE46005.1
Succinate dehydrogenase subunit B.
   
 
 0.555
SDE51291.1
methylmalonyl-CoA mutase.
    
 0.522
Your Current Organism:
Bhargavaea beijingensis
NCBI taxonomy Id: 426756
Other names: B. beijingensis, Bacillus beijingensis, Bacillus beijingensis Qiu et al. 2009, Bacillus sp. ge09, Bacillus sp. ge10, Bhargavaea beijingensis (Qiu et al. 2009) Verma et al. 2012, CGMCC 1.6762, DSM 19037, strain ge10
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