STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsbWSerine/threonine-protein kinase RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). (157 aa)    
Predicted Functional Partners:
SDE71454.1
RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family.
 
 0.998
SDE71507.1
Anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.979
SDE71537.1
sigma-B regulation protein RsbU (phosphoserine phosphatase).
 
 0.957
SDE71428.1
Negative regulator of sigma-B (phosphoserine phosphatase).
 
 0.941
SDE71593.1
rsbT antagonist protein RsbS.
 
 
 0.895
SDE71623.1
rsbT co-antagonist protein RsbR.
 
 
 0.894
SDE17029.1
RNA polymerase, sigma subunit, RpoX/SigF; Belongs to the sigma-70 factor family.
 
 
 0.889
SDE92263.1
Protease I.
   
    0.821
SDE23353.1
PAS domain S-box-containing protein.
  
 
 0.798
SDE17088.1
Anti-anti-sigma regulatory factor, SpoIIAA; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.749
Your Current Organism:
Bhargavaea beijingensis
NCBI taxonomy Id: 426756
Other names: B. beijingensis, Bacillus beijingensis, Bacillus beijingensis Qiu et al. 2009, Bacillus sp. ge09, Bacillus sp. ge10, Bhargavaea beijingensis (Qiu et al. 2009) Verma et al. 2012, CGMCC 1.6762, DSM 19037, strain ge10
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