STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
luxSS-ribosylhomocysteine lyase /quorum-sensing autoinducer 2 (AI-2) synthesis protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (158 aa)    
Predicted Functional Partners:
mtnN
Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
 
 
 0.980
SEJ52874.1
Tetratricopeptide repeat-containing protein.
     
 0.941
SEI79600.1
O-acetylserine dependent cystathionine beta-synthase.
 
 
 0.936
SEI79566.1
Cystathionine gamma-lyase / homocysteine desulfhydrase.
  
 
 0.922
SEI98210.1
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.917
SEJ88235.1
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.917
SEJ71601.1
Cystathionine gamma-synthase.
  
 
 0.911
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
  
  0.910
SEI98252.1
Homoserine dehydrogenase.
     
 0.904
SEI98282.1
O-acetylhomoserine (thiol)-lyase.
     
 0.901
Your Current Organism:
Bhargavaea ginsengi
NCBI taxonomy Id: 426757
Other names: B. ginsengi, Bacillus ginsengi, Bacillus ginsengi Qiu et al. 2009, Bacillus sp. ge14, Bacillus sp. ge15, Bhargavaea ginsengi (Qiu et al. 2009) Verma et al. 2012, CGMCC 1.6763, DSM 19038, strain ge14
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.