STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS76059.1Putative permease; KEGG: bcz:BCZK0244 4.3e-115 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; COG: COG2252 Permeases; Psort location: CytoplasmicMembrane, score: 9.99. (438 aa)    
Predicted Functional Partners:
EDS74839.1
Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.874
EDS76060.1
Hypothetical protein.
       0.773
pdxB-2
KEGG: cff:CFF8240_1663 1.6e-67 hprA; glycerate dehydrogenase K00018; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.647
EDS74706.1
Macro domain protein; KEGG: bur:Bcep18194_A6181 7.7e-22 Appr-1-p processing enzyme family K00985; COG: COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; Psort location: Cytoplasmic, score: 8.87.
      0.576
EDS76061.1
Transposase; COG: COG3547 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score: 8.87.
       0.540
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.540
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.521
EDS75028.1
Hypothetical protein; KEGG: lsl:LSL_1510 5.2e-16 pncA; pyrazinamidase / nicotinamidase K01463:K01440; COG: COG1335 Amidases related to nicotinamidase.
    
  0.497
purD
KEGG: pca:Pcar_2231 2.7e-106 phosphoribosylamine--glycine ligase K01945; COG: COG0151 Phosphoribosylamine-glycine ligase; Psort location: Cytoplasmic, score: 8.87; Belongs to the GARS family.
  
  
 0.491
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: gka:GK0265 2.7e-106 phosphoribosylaminoimidazole synthetase K01933; COG: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; Psort location: CytoplasmicMembrane, score: 7.80.
  
  
 0.473
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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